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KMID : 0928320080080030150
Korean Journal of Health Promotion and Disease Prevention
2008 Volume.8 No. 3 p.150 ~ p.157
Changes of Blood Oxidative Stress Markers after a High-Intensity Exercise in Young Women
Joo Mi-Hyun

Abstract
Background: It is reported that high-intensity physical exercise may induce oxidative stress. Therefore, the purpose of this study was to investigate the change of blood oxidative stress markers after a high-intensity exercise in young women

Methods: Eight sedentary women who have regular menstrual cycles participated in this study. Regular menstrual cycles were determined by basal body temperature (BBT) and urinary ovulation test for 2 mouths prior to this study. All subjects performed the bicycle ergometer exercise (for 22.5 min at 80% VO2max). Lactate was determined from blood of Pre-and Post-exercise (PO). Blood oxidative stress markers (erythrocyte thiobarbituric acid reactive substances: TBARS, Superoxide dismutase: SOD, Glutathione Peroxidase: GPx and serum Creatine PhosphoKinase: CPK) were determined from blood of Pre- and Post-exercise (PO, P2, P12 and P24).

Results: In this results, lactate was increased clearly at the P0 compared with Pre (p<0.05). And TBARS increased significantly P12 compared with Pre (p<0.05). SOD activity also decreased significantly P24 compared with Pre (p<0.05). However, GPx activity did not show statistically significant changes by the high-intensity exercise. CPK significantly decreased P0 and increased significantly P12 compared with Pre (p<0.05).

Conclusions: In the menses, high-intensity exercise may increase the blood oxidative stress in the young woman which has a normal menstrual cycle. In particular, the influence of ROS is very high after P12. Therefore, sedentary women had better do not intense exercise in the menses.
KEYWORD
High-intensity exercise, Oxidative stress, Young woman
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